Specifications

Variant Details
Catalog IDbs-12523R-Cy5-100ULSupplier Catalog IDbs-12523R-Cy5-100UL
Size100 µlPrice N/A
Supplier N/A Package Content ARL4 Polyclonal Antibody, Cy5 Conjugated, 100ul
General
AntigenARL4AClonalityPolyclonal
HostRabbitReactivityHuman, Mouse, Rat
ApplicationsImmunofluorescence, ImmunohistochemistryConjugatedConjugated
Conjugate TypeCy (Cyanine)Specific ConjugateCy5
IsotypeIgGImmunogenKLH conjugated synthetic peptide derived from human ARL4
Concentration1µg/µlDilutionIF(IHC-P)(1:50-200)
Purification MethodPurified by Protein A.GeneARL4
Gene ID10124 (Homo sapiens)Alternative Names & SynonymsADP ribosylation factor like 4A; ADP-ribosylation factor-like protein 4A; ARL 4; ARL4A; ARL4A_HUMAN.
Storage & HandlingStore at 4°C for 12 monthsStorage BufferAqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide

Description

ADP-ribosylation factors (ARFs) are highly conserved guanine nucleotide-binding proteins that enhance the ADP-ribosyltransferase activity of cholera toxin. ARF抯 are important in eukaryotic vesicular trafficking pathways and activating phospholipase D. ARL4 (ADP-ribosylation factor-like protein 4A) is a member of the ARF-like protein (ARL) subfamily of small GTPases. It contains a C terminal nuclear localization signal (NLS) region that interacts with Importin-? ARL4 localizes to the nucleus and is found in a variety of tissues, but is predominantly expressed in spermatogonia and Sertoli cells. It is most closely related to ARL6 and ARL7. Unlike ARFs, ARL4 does not activate the cholera toxin ADP-ribosyltranferase. ARL4 may play a role in neurogenesis during embryonic development and somitogenesis in the early stages of adult spermatogenesis.

For research use only.

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