The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene. [provided by RefSeq, Jul 2008]Applications: Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry. Other applications not tested.Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note:Applications are based on unconjugated antibody.Note: Applications are based on unconjugated antibody.
|Catalog ID||210329-FITC-100UL||Supplier Catalog ID||210329-FITC-100UL|
|Supplier||N/A||Package Content||Rabbit Anti-human CTSE polyclonal antibody SKU:210329-FITC, 100 µl|
|Reactivity||Human||Cross Reactivity||Human, Mouse, Rat|
|Applications||Immunocytochemistry, Immunofluorescence, Western Blot||Conjugated||Conjugated|
|Conjugate Type||FITC (Fluorescein isothiocyanate)||Isotype||IgG|
|Immunogen||Recombinant protein corresponding to human CTSE.||Specificity||Recognizes CTSE.|
|Dilution||Western Blot: 1:500-1:2000Immunohistochemistry: 1:50-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.||Purification Method||Purified by affinity chromatography.|
|Additional Information||Applications are based on unconjugated antibody.||Form||Liquid|
|Shipping Temperature||Blue Ice||Storage & Handling||-20°C|
For research use only.