Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a KrÃ¼ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF266 is a 549 amino acid nuclear protein belonging to the KrÃ¼ppel C2H2-type zinc finger protein family. ZNF266 has one KRAB domain and fourteen C2H2 zinc fingers. Due to the presence of these domains, ZNF266 is thought to be involved in transcriptional regulation. Repression of ZNF266 results in the blocking of erythroid differentiation and partial blocking of megakaryocytic differentiation, possibly indicating a role in the differentiation of erythroids and megakaryocytes.
|Catalog ID||bs-12215R-Cy3-100UL||Supplier Catalog ID||bs-12215R-Cy3-100UL|
|Supplier||N/A||Package Content||ZNF266 Polyclonal Antibody, Cy3 Conjugated, 100ul|
|Conjugate Type||Cy (Cyanine)||Specific Conjugate||Cy3|
|Isotype||IgG||Immunogen||KLH conjugated synthetic peptide derived from human ZNF266|
|Purification Method||Purified by Protein A.||Gene||ZNF266|
|Gene ID||10781 (Homo sapiens)||Alternative Names & Synonyms||HZF1; KIAA2007; Zinc finger protein 1; Zinc finger protein 266; Zinc finger protein HZF1; Zinc finger protein HZF1; ZN266_HUMAN; ZNF 266; ZNF266.|
|Storage & Handling||Store at 4°C for 12 months||Storage Buffer||Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide|