Specifications

Variant Details
Catalog IDbs-12215R-Cy3-100ULSupplier Catalog IDbs-12215R-Cy3-100UL
Size100 µlPrice N/A
Supplier N/A Package Content ZNF266 Polyclonal Antibody, Cy3 Conjugated, 100ul
General
AntigenZNF266ClonalityPolyclonal
HostRabbitReactivityHuman
ApplicationsImmunofluorescence, ImmunohistochemistryConjugatedConjugated
Conjugate TypeCy (Cyanine)Specific ConjugateCy3
IsotypeIgGImmunogenKLH conjugated synthetic peptide derived from human ZNF266
Concentration1µg/µlDilutionIF(IHC-P)(1:50-200)
Purification MethodPurified by Protein A.GeneZNF266
Gene ID10781 (Homo sapiens)Alternative Names & SynonymsHZF1; KIAA2007; Zinc finger protein 1; Zinc finger protein 266; Zinc finger protein HZF1; Zinc finger protein HZF1; ZN266_HUMAN; ZNF 266; ZNF266.
Storage & HandlingStore at 4°C for 12 monthsStorage BufferAqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide

Description

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF266 is a 549 amino acid nuclear protein belonging to the Krüppel C2H2-type zinc finger protein family. ZNF266 has one KRAB domain and fourteen C2H2 zinc fingers. Due to the presence of these domains, ZNF266 is thought to be involved in transcriptional regulation. Repression of ZNF266 results in the blocking of erythroid differentiation and partial blocking of megakaryocytic differentiation, possibly indicating a role in the differentiation of erythroids and megakaryocytes.

For research use only.

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